25 Bible Verses For Depression and Hopelessness

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Today we will be dealing with 25 Bible verses for depression and hopelessness. The world is changing at a fast pace and the enemy is rapidly taking stock, inflicting people with different kinds of epidemic and psychological diseases. We have read and seen too many people kill themselves due to depression. As it is now, depression is the biggest cause of suicide all over the globe. And while most people still don’t believe there’s anything called depression, the suicide rate continues to gain weight.

Depression is a state of hopelessness. One thing that still keeps many people alive today is hope. When hope is lost, a man loses the essence of living. He doesn’t see any need to strive or fight. Such a man will give in to any demon or problem tormenting him. And when this happens, the enemy is happy. Hopelessness is a state of faithlessness. When faith is lost in one person we believe could help us, hope will die. And when this happens, a man will slip into depression.

Meanwhile, this is not part of God’s plan for our lives. The scripture made us understand that God will not tempt us beyond what our faith can carry. So our state of hopelessness and depression doesn’t interest God. It doesn’t make God happier. The devil loves it better when our hope is lost. Only God can heal a man living in depression. Only God can make a hopeless man still find a reason to keep living. The word of God is potent in helping us find answers where we least expected.

We have compiled a list of 25 Bible verses for depression and hopelessness. It will help many of us battling depression and hopelessness.


1. Deuteronomy 31:8

It is the Lord who goes before you. He will be with you; he will not leave you or forsake you. Do not fear or be dismayed.


2. Isaiah 41:10

fear not, for I am with you; be not dismayed, for I am your God; I will strengthen you, I will help you, I will uphold you with my righteous right hand.


3. Psalm 40:1-3

I waited patiently for the Lord; he inclined to me and heard my cry.

He drew me up from the pit of destruction, out of the miry bog, and set my feet upon a rock, making my steps secure. He put a new song in my mouth, a song of praise to our God.


4. Psalm 3:3

But you, O Lord, are a shield about me, my glory, and the lifter of my head.


5. Psalm 34:18-19

The Lord is near to the brokenhearted and saves the crushed in spirit.

Many are the afflictions of the righteous, but the Lord delivers him out of them all


6. Isaiah 40:31

The Lord Will Renew Your Strength

…but they who wait for the Lord shall renew their strength; they shall mount up with wings like eagles; they shall run and not be weary; they shall walk and not faint.


7. Isaiah 42:3

a bruised reed he will not break, and a faintly burning wick he will not quench; he will faithfully bring forth justice.


8. Matthew 11:28-30

Come to me, all who labor and are heavy laden, and I will give you rest. Take my yoke upon you, and learn from me, for I am gentle and lowly in heart, and you will find rest for your souls. For my yoke is easy, and my burden is light.


9. Romans 8:38-39

For I am sure that neither death nor life, nor angels nor rulers, nor things present nor things to come, nor powers, nor height nor depth, nor anything else in all creation, will be able to separate us from the love of God in Christ Jesus our Lord.


10. Psalm 34:17

The Lord Hears Your Cry

When the righteous cry for help, the Lord hears and delivers them out of all their troubles.


11. Psalm 42:11

Why are you cast down, O my soul and why are you in turmoil within me? Hope in God; for I shall again praise him, my salvation and my God.


12. 2 Corinthians 1:3-4

Blessed be the God and Father of our Lord Jesus Christ, the Father of mercies and God of all comfort, who comforts us in all our affliction, so that we may be able to comfort those who are in any affliction, with the comfort with which we ourselves are comforted by God.


13. Philippians 4:6-7 

Do not be anxious about anything, but in everything by prayer and supplication with thanksgiving let your requests be made known to God. And the peace of God, which surpasses all understanding, will guard your hearts and your minds in Christ Jesus.


14. Psalm 23:4 

Even though I walk through the valley of the shadow of death, I will fear no evil, for you are with me; your rod and your staff, they comfort me.


15. Romans 8:28 

And we know that for those who love God all things work together for good, for those who are called according to his purpose.


16. Romans 8:24-26

For in this hope we were saved. Now hope that is seen is not hope. For who hopes for what he sees? But if we hope for what we do not see, we wait for it with patience. Likewise the Spirit helps us in our weakness. For we do not know what to pray for as we ought, but the Spirit himself intercedes for us with groanings too deep for words.


17. Psalm 9:10-11

And they that know thy name will put their trust in thee: for thou, LORD, hast not forsaken them that seek thee. Sing praises to the LORD, which dwelleth in Zion: declare among the people his doings.


18. Psalm 37:28

For the LORD loves justice And does not forsake His godly ones; They are preserved forever, But the descendants of the wicked will be cut off.


19. Deuteronomy 31:8

“The LORD is the one who goes ahead of you; He will be with you. He will not fail you or forsake you. Do not fear or be dismayed.


20. Isaiah 54:4

“Do not be afraid; you will not be put to shame. Do not fear disgrace; you will not be humiliated. You will forget the shame of your youth and remember no more the reproach of your widowhood.”



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